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Be sure to contact your healthcare provider promptly if you have any of the following:
- Heavy Bleeding. Contact your healthcare provider right away if you bleed enough to soak through two thick full-size sanitary pads per hour for two consecutive hours or if you are concerned about heavy bleeding. In about 1 out of 100 women, bleeding can be so heavy that it requires a surgical procedure (surgical aspiration or D&C).
- Abdominal Pain or “Feeling Sick.” If you have abdominal pain or discomfort, or you are “feeling sick,” including weakness, nausea, vomiting, or diarrhea, with or without fever, more than 24 hours after taking misoprostol, you should contact your healthcare provider without delay. These symptoms may be a sign of a serious infection or another problem (including an ectopic pregnancy, a pregnancy outside the womb).
- Fever. In the days after treatment, if you have a fever of 100.4°F or higher that lasts for more than 4 hours, you should contact your healthcare provider right away. Fever may be a symptom of a serious infection or another problem
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* The information on this page is a summary and is not intended to cover all available information about this product. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of our healthcare professional.
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What is Mifeprex used for
Mifeprex (mifepristone) is primarily used in a two-drug regimen with misoprostol for a medical abortion (termination of an early pregnancy). It is also used under a different brand name (Korlym) to manage high blood sugar in certain patients with Cushing’s syndrome. Mifeprex, when used with misoprostol, is approved by the FDA to end an intrauterine pregnancy through 70 days of gestation (10 weeks or less since the first day of the last menstrual period.
- How it works: Mifepristone is an antiprogestin medication that blocks the hormone progesterone, which is necessary for a pregnancy to continue. This causes the lining of the uterus to thin and prevents the embryo from remaining implanted. The second medication, misoprostol, taken 24 to 48 hours later, causes the uterus to contract and expel the pregnancy tissue, similar to an early miscarriage.
- Effectiveness: When used correctly in this regimen, it is highly effective, with success rates of about 94-98% in the first 8 weeks of pregnancy.
- Administration: It is a prescription drug available through a restricted program (Mifepristone REMS Program) to ensure patient safety and proper usage.
Mifeprex dosage
Mifepristone and misoprostol are used in combination primarily for medical abortion and management of early pregnancy loss. Mifepristone is also used alone in a different dosage to manage hyperglycemia in patients with Cushing’s syndrome.
mifeprex side effects
The side effects vary depending on its use (e.g., medical abortion or treating Cushing’s syndrome). The most common side effects when used in combination with misoprostol for a medical abortion are cramping, vaginal bleeding, nausea, and diarrhe
What is the most important information I should know about Mifeprex?
What symptoms should I be concerned with?
Although cramping and bleeding are an expected part of ending a pregnancy, rarely, serious and potentially life-threatening bleeding, infections, or other problems can occur following a miscarriage, surgical abortion, medical abortion, or childbirth. Seeking medical attention as soon as possible is needed in these circumstances. Serious infection has resulted in death in a very small number of cases. There is no information that use of Mifeprex and misoprostol caused these deaths. If you have any questions, concerns, or problems, or if you are worried about any side effects or symptoms, you should contact your healthcare provider.
Mifeprex risk
Mifeprex (mifepristone), used in a regimen with misoprostol for medical abortion, is considered very safe by major medical organizations such as the FDA and ACOG. Serious risks are rare, occurring in less than 1% of patients, and are comparable to those associated with spontaneous or surgical abortion.
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Frequently asked questions
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Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.

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