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Formulation-Specific Side Effects

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The most common serious adverse reactions are respiratory depression, apnea, rigidity, and bradycardia. Other reported effects include hypertension, hypotension, dizziness, blurred vision, nausea, vomiting, diaphoresis, pruritus, urticaria, laryngospasm, and anaphylaxis

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Exposure of the application site to direct external heat sources has resulted in fatal overdose, as heat significantly increases fentanyl absorption.

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Fentanyl OTFC (eg, Actiq) contains sugar. Cavities and tooth decay can happen in people taking OTFC. When taking OTFC, you should talk to your dentist about proper care of your teeth.

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Does Ritalin interact with other medicines (drug interactions)?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before taking methylphenidate.

  • A monoamine oxidase inhibitor (MAOI) within the past two weeks, which is a medicine usually used for depression or Parkinson’s disease
  • A medicine for high or low blood pressure
  • Risperidone, which is a medicine used to treat schizophrenia, bipolar disorder, and crankiness seen with autism
  • An H2 blocker, such as cimetidine (Tagamet), famotidine (Pepcid), ranitidine (Zantac), or nizatidine (Axid)
  • A proton pump inhibitor (PPI), such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or rabeprazole (Aciphex)
  • Warfarin, which is a blood thinner
  • Any medicine for seizures, such as phenobarbital, phenytoin, or primidone
  • A tricyclic antidepressant, such as amitriptyline, nortriptyline, or protriptyline, even if it is not used for depression
  • A selective serotonin reuptake inhibitor (SSRI), such as fluoxetine, paroxetine, or sertraline, which is a medicine commonly used for anxiety and depression
  • An anesthetic, which is a medicine that is used to put you to sleep before surgery

This may not be a complete list of medicines that can interact with methylphenidate. Always check with your health care provider.

Does Methylphenidate (Concerta, Ritalin, and others) interact with other drugs you are taking?

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What should I do if I accidentally use too much Ritalin?

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What should I do if I miss a dose of Ritalin?

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Recovery and Outlook

When should I call my healthcare provider?

It’s important to see your healthcare provider regularly so they can make sure your treatment is working.

Call your provider if you have:

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  • Signs of low blood sugar like shaking and sweating
  • Health changes like surgery, pregnancy or new medications

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What else should I know about sulfonylureas?

This class of drugs may be less effective over time. If this happens, your provider will recommend another treatment. Keeping your follow-up appointments and monitoring your blood sugar can help you detect if the medication is still working well.

Knowing the signs of low blood sugar is also helpful when you take sulfonylureas. Early signs include:

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Is Vyvanse taken long term?

Yes, Vyvans is usually taken as a long-term treatment. If you and your doctor determine that Vyvans is safe and effective for you, it’s likely that you’ll take it long term.

Your doctor will discuss the safety of taking Vyvanse long term with you.

Dosage adjustments

In some cases, your doctor may adjust your Vyvanse dosage outside of the usual increase that occurs at the beginning of treatment.

Reasons to increase or decrease your dosage include:

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