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Before taking this medicine

You should not use this medicine if you are allergic to it, or if you have:

  • severe asthma or breathing problems; or
  • a blockage in your stomach or intestines.

This medicine may cause a life-threatening heart rhythm disorder. Your heart function may need to be checked during treatment.

To make sure methadone is safe for you, tell your doctor if you have ever had:

  • heart problems, long QT syndrome (in you or a family member);
  • breathing problems, sleep apnea;
  • a head injury, brain tumor, or seizures;
  • drug or alcohol addiction, or mental illness;
  • liver or kidney disease;
  • urination problems; or
  • problems with your gallbladder, pancreas, or thyroid.

Tell your healthcare provider if you notice your pain getting worse. If your pain gets worse after you take methadone hydrochloride tablets, do not take more methadone hydrochloride tablets without first talking to your healthcare provider. Talk to your healthcare provider if the pain that you have increases, if you feel more sensitive to pain, or if you have new pain after taking methadone hydrochloride tablets.

Pregnancy

Talk to your doctor before using opioid medicine if you are pregnant or planning a pregnancy. If you use opioid medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, called neonatal opioid withdrawal syndrome (NOWS), which is treatable, and your baby may need medical treatment for several weeks.

Breastfeeding

Ask a doctor before using opioid medicine if you are breastfeeding. This medicine passes into breast milk and may harm your baby. Tell your doctor immediately if you notice increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness in the nursing baby. Talk to your baby's doctor when you decide to wean your baby. It is important to wean your baby gradually so that your baby does not develop withdrawal symptoms when he or she stops receiving methadone in breastmilk.

 

 

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