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Warnings & Precautions
Who should not use promethazine/codeine?
Allergies to Ingredients. People who are allergic to any of the following should not take promethazine/codeine.
- Promethazine
- Codeine
- Phenergan with Codeine
- Any other medicine known as an opioid
- Any of the ingredients in the specific product dispensed
Your pharmacist can tell you all of the ingredients in the specific promethazine/codeine products they stock. buy ACTAVIS syrup/codeine
Drug Interactions. Promethazine/codeine should not be taken while you are using certain other medicines. Before taking promethazine/codeine, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using or have used recently. See the Interactions section for more details.
Children. Promethazine/codeine should not be use
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Before taking this medicine
You should not use this medicine if you are allergic to it, or if you have:
- severe asthma or breathing problems; or
- a blockage in your stomach or intestines.
This medicine may cause a life-threatening heart rhythm disorder. Your heart function may need to be checked during treatment.
To make sure methadone is safe for you, tell your doctor if you have ever had:
- heart problems, long QT syndrome (in you or a family member);
- breathing problems, sleep apnea;
- a head injury, brain tumor, or seizures;
- drug or alcohol addiction, or mental illness;
- liver or kidney disease;
- urination problems; or
- problems with your gallbladder, pancreas, or thyroid.
Tell your healthcare provider if you notice your pain getting worse. If your pain gets worse after you take methadone hydrochloride tablets, do not take more methadone hydrochloride tablets without first talking to your healthcare provider. Talk to your healthcare provider if the pain that you have increases, if you feel more sensitive to pain, or if you have new pain after taking methadone hydrochloride tablets.
Pregnancy
Talk to your doctor before using opioid medicine if you are pregnant or planning a pregnancy. If you use opioid medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, called neonatal opioid withdrawal syndrome (NOWS), which is treatable, and your baby may need medical treatment for several weeks.
Breastfeeding
Ask a doctor before using opioid medicine if you are breastfeeding. This medicine passes into breast milk and may harm your baby. Tell your doctor immediately if you notice increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness in the nursing baby. Talk to your baby's doctor when you decide to wean your baby. It is important to wean your baby gradually so that your baby does not develop withdrawal symptoms when he or she stops receiving methadone in breastmilk.
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What are some other side effects of Nembutal?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling sleepy.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Nembutal?
- If you need to store (pentobarbital) at home, talk with your doctor, nurse, or pharmacist about how to store it.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about (pentobarbital), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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Formulation-Specific Side Effects
Injectable Fentanyl (IV/IM), such as Sublimaze
The most common serious adverse reactions are respiratory depression, apnea, rigidity, and bradycardia. Other reported effects include hypertension, hypotension, dizziness, blurred vision, nausea, vomiting, diaphoresis, pruritus, urticaria, laryngospasm, and anaphylaxis
Fentanyl Transdermal Patch
Possible side effects of the fentanyl transdermal patch (eg, Duragesic) include respiratory depression, sedation, constipation, nausea, and skin reactions at the application site.
Exposure of the application site to direct external heat sources has resulted in fatal overdose, as heat significantly increases fentanyl absorption.
Fentanyl Oral Transmucosal Lozenge (OTFC)
Fentanyl OTFC (eg, Actiq) contains sugar. Cavities and tooth decay can happen in people taking OTFC. When taking OTFC, you should talk to your dentist about proper care of your teeth.
Possible side effects are similar to other transmucosal formulations and include respiratory depression, sedation, nausea, dizziness, and oral mucosal irritation.
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The possible side effects of fentany buccal or sublingual tablets (eg, Fentora) are similar to other transmucosal formulations, such as respiratory depression, nausea, dizziness, and headache.
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The possible side effects of fentany nasal spray include respiratory depression, nasal irritation, nausea, dizziness, and somnolence.
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Addiction recovery medicines